To observe the human embryonic olfactory ensheathing cells (olfactory) cytologic features of cell transplantation in adult rat spinal cord regeneration of axons. Isolation, Purification and cultivate human embryonic olfactory will olfactory transplantation of human embryo to adult rats T10 half of the thoracic spinal cord ends. Six weeks after the spinal cord was observed olfactory distribution.
Results of human olfactory cells and transplant rejection is closely related to the signs : HLA-DR, B7-1 (CD80). B7-2 (CD86), CD40 and CD40L were negative. One-way mixed lymphocyte reaction shows human embryonic olfactory ensheathing cells on mixed lymphocyte reaction no obvious boost. Olfactory mainly in the white matter to the end and the tail end of the first movement, olfactory and good integration of the host tissue. Some long-axon regeneration stump intergovernmental organizations, MBP was positive. Conclusion : human embryonic rat olfactory right into spinal cord after injury to promote axonal regeneration role.
المزيد من المستخلصات حول Human embryo implantation olfactory ensheathing cells to repair spinal cord injury in the preliminar